Aim. To study the continuity of the provision of services in PHC facilities and the level of primary morbidity among young people in the Republic of Tajikistan.
Material and methods. Analyzed the data of the Republican Center for Medical Statistics and Information of the Ministry of Health and Social Development; reports of the Republican, regional and district centers of reproductive health; Republican Center for the Prevention and Control of AIDS; reports of the Youth Medical Advisory Department; data from outpatient records (form 025 / k - an individual card of a patient using contraceptives; form 112 / y - an individual patient record), as well as an analysis of the questionnaires developed by us. The rate of primary morbidity was calculated per 1000 people of the population: Level of primary morbidity = Number of first visits for diseases newly diagnosed this year / Average annual population * 1000.
Results. Average level of general primary morbidity in 2018-2019 amounted to 638%o among the youth of the Republic of Tajikistan aged 15 to 30 years, while this indicator among boys was 778.2%o and among girls - 4392.5%o.
Conclusions. A well-functioning system of referrals ensures the continuity of the provision of the necessary preventive and treatment-diagnostic services to young people, thereby increasing their availability, evidence-based prescriptions and providing an economic effect.
Purpose of the study. Study of the state and prospects of development of the private sector in the Kabul city health management system.
Material and methods. The research material is based on consolidated data of annual reports of medical and preventive treatment facilities of the city of Kabul, the IGA, which switched to new methods of financing in the period 2003-2021.
Results. The potential of a private health care system in Kabul is not demanded by the state. The public health system in Kabul is characterized by the dominance of the public sector with an emerging upward trend in the private sector.
Conclusion. The health care system of Kabul, the is multi-structured, consists of the public and private sectors with a predominance of the private. Government health policy is aimed at expanding the private sector, but under tight government regulation. The main obstacles in the development of private sector of healthcare of Kabul city are: lack of security, poverty of the population, imperfect regulatory documents, lack of a proper regulatory legal base.
Purpose of the study. To study the laboratory and clinical characteristics of pregnant women with obesity.
Material and research methods. A total of 139 patients were examined, including 109 pregnant women with obesity (main group). This group, in turn, is divided into three subgroups: obese - 40 patients, obesity + preeclampsia - 39 patients and obesity + insulin resistance - 30 patients. The control group was formed from among healthy pregnant women - 30 patients. The results of the obtained data were processed by the method of variational and descriptive statistics using the Student’s criteria, the Mann-Whitney U-rank test. Qualitative comparisons of populations were performed using chi-square analysis, corrected if necessary by Yates.
Research results. The results of our study showed that the predominant majority of pregnant women with obesity were in active reproductive age - 73.6% and in late reproductive age - 26.4% of women, respectively (Figure 1). At the same time, out of the total number of women in adolescence (18-19 years), there were two (1.8%) obese pregnant women.
Conclusion. The results of our study showed that in pregnant women with obesity, there is a gradual deterioration in lipid and carbohydrate metabolism parameters with the progression of pregnancy, which adversely affect perinatal outcomes. The Homa index can be used as a marker of insulin resistance indicating a change in carbohydrate metabolism in obese women.
The aim of the study: Improvement of early diagnosis and treatment of relatively rare pathology of trichobezoar, as well as related complications in children.
Material and methods of research. A clinical analysis of the diagnosis of the treatment of trichobezoars in children was carried out based on the materials of the Department of Pediatric Surgery of the SI “Istiqlol Health Complex” for the period 2016-2021. We have 2 observations, in which all were girls aged 12-14 years. Among the instrumental diagnostic methods, ultrasound of the abdominal cavity, stomach X-ray and Esophagogastroduodenoscopy were used.
The results of the study and their discussion. A clinical analysis of the diagnosis and treatment of 2 girls aged 12-14 years, who are in Department of pediatric surgery of the SI “Istiqlol Health Complex” for the period 2016-2021 with a diagnosis of trichobezoars was carried out. Surgical treatment was performed. During the revision, a dense conglomerate of large dimensions (20 x 8 x 8 cm) was found in the stomach cavity and a foreign body was removed. The postoperative period proceeded smoothly; the girls were discharged in a satisfactory condition under the outpatient supervision of neuropsychiatrists.
Aim. Wink introkordias hemodynamics of the heart in women with acute myocardial infarction in climacteric period
Material and methods. The results of the spectral analysis of the variation of the cardiac interval in 125 women were analyzed by the echokardiografi metod. Uritsky conditionally divided into 3 groups: 1 group - 25 (20%) control grup thy women; Group 2- 45 (36%) women with acute myocardial infarction in menopause without complications; Group 3- 55 (44%) women with acute myocardial infarction in menopause with complications.
Purprose of the study. The aim of the work was the sanitary and hygienic assessment of water bodies of the republic with justification of priority measures aimed at their protection and preservation of public health.
Materials and research methods. We have applied the Long-term data bank on the natural and climatic characteristics of the water basin, their natural hydro chemical characteristics, technogenic and anthropogenic pollution. Results of chemical and microbiological studies of water samples of SESC from water bodies of Tajikistan for 2014-2016.
Results and its discussion. When analyzing the qualitative composition of surface waters according to the index of water pollution, it was revealed that according to the degree of pollution, the water bodies of the republic can be conditionally divided into four classes of water quality (from moderately polluted to very dirty, i.e. III-VI classes). The main sanitary indicators of the water quality of the rivers of Tajikistan indicate that for many of them it does not correspond to the hygienic standards for water bodies used as sources of drinking water supply.
Conclusions. Thus, based on everything, it should be noted that the introduction of biogasification plants will solve the problem of disposal and disinfection of huge masses of household waste in rural areas, which is of great sanitary and hygienic, socio-economic and environmental significance.
Purpose of the study. To show the limited living conditions of the mountain ranges of Tajikistan and their special need to improve cultural and living environments through the electrification of villages.
Material and research methods. Thelarge practical materials including current archives of regions and districts, monographic studies of periodicals on the electrification of mountain ranges and the South-Eastern regions of Tajikistan have been collected and analyzed from archives.
Research results and their discussian. The fact of limited work of Tajik electric power engineers on electrification of mountain massifs, cultural and everyday spheres of life of rural residents of mountain massifs are proved.
Conclusionp.The huge positive and effective successes have been achieved in the electrification of mountain massifs, the application of electrification of cultural and everyday spheres of life of rural - mountain massifs.
The purpose of the analysis: Familiarization with the activities of the library of the NEI “Medical - Social Institute Tajikistan” in promoting the educational process.
Materials and methods of analysis: Analytical materials are the plan, reports of the library, as well as the library fund, through which users can learn about the activities of the library, its history, present and future.
The result of the analysis: In the process of analysis, the main library was determined over the years of its activity, how propaganda work is carried out in the library. As well as the growth of his fund in what situation today, users can find out through this article.
Conclusion: Today’s librarian must fulfill the task of Informant and information, programmer, so that in the learning process it can serve students introduce them to the latest materials. Students should definitely learn how to find materials on medical websites on their own, and librarians should help them with this.
Purprose of the study. This article considers the concept and content of the social function of the modern Republic of Tajikistan in a market economy, as well as understanding the importance of social functions for the state and for citizens.
Material and methods. In the course of the study, the normative legal acts of the Republic of Tajikistan were widely used, their in-depth analysis and comparison were carried out.
Results. First of all, the level of attention of the state to the social sphere is determined, several measures are proposed to increase the level of social functions of the state.
Conclusion. In the article, special attention was paid to the consideration of social problems in the modern era, when the Republic of Tajikistan was in a financial and economic crisis, and we determined that it is the implementation of state social functions that is decisive for the development of the economy.
Purprose of the study. Identification of the pharmacological activity and catalytic ability of 8-choloro2-methyl-benzol [4,5] thiazolo[3,2-a] pyrimidin -4 Ona
Materials and research methods. The Buch is the formation of C-N bonds via a palladium cross-coupling reaction between amines and aryl-substituted holides, has also worked wel with various amines and aryl- substituted holides, i.e.8-chloro-2-methylbenzo[4,5] thiazolo [3,2-a] pyrimidin-4 ona with morpholine as a catalyst Pd (dba) CHCL3 (4, mol%), XPhos ligand (8, mol%) base Na ot Bu, (1,4, equiv) and refluxing in toluene (2 ml) for 16 hours gave 8- morpholino -2- methylbenzo [4,5] thiazolo [3,2-a] 4-ona amounted to 85% and for other amines of the cross- coupling products it was as a percentage: 52 (8 phenylmenthylamino), 72 (8-fluovopheylamino) 56 (8-(3,5- thymenthoxyphenylamino)-2 methylbenzo [4,5] thiazolo [3,2] pyrimidin-4 ona
Results and its discussion. Benzothiazolo [3,2-a] pyrimidin has a wide vange of pharmacological activites, such as: antileishmanial, sedative and antifungal. The Buchwoid – Hartwing cross –coupling reaction between amines and aryl-substitutcal halides, also worked weii with varios amines and heteryl halides, i.e. 8-chloro-2-methylbenzo[4,5]thiazolo[3,2-a] pyridin -4 ona was 85% and for other amines of cross-coupling products was%: 52 (8-phenylmethylamino) 72 (8-fluorophenylamino), 56 (8-(3-trifluoromethylphenylamino) and 63 (8-(3,5- thymethoxyphenylamino)-2-methylbenzo[4,5]thiazolo [3,2-a] pyrimidine -4 ona
Conclussion. 1) Benzothiazolo [3,2-a] pyridine has broad pharmacological activities (antibacterial, antitumor, fungicial, antileishmanial, sedative and antifungal). 2) The Buchnald-Hartwig cross-coupling reaction, which worked well with various amines and halides, i.e. 8-chloro 2- methylbenzo [4,5] gnatolo [3,2-a] pyrimidin – 4 ona. 3) The best results were obtained using Pol (dba) – X CHCl as a catalyst. X Phos as ligand and NaOrBu as base in toluene. The reaction with morpholine gave the product 2 a in 85% yield.
